Which statement about cells that can divide indefinitely used for standard assays is correct?

Which statement about cells that can divide indefinitely used for standard assays is correct?

• A. Immortalized cells
• B. Primary cells
• C. In Vivo Tests
• D. In Vitro Tests

Answer: (A)

The concept here is that some cell lines can keep dividing without hitting the normal aging limit, making them ideal for standard laboratory tests. Immortalized cells are altered so they bypass replicative senescence, often through mechanisms like telomerase activation or viral oncogene expression. This gives them a nearly endless supply and highly consistent behavior across many passages, which is exactly what researchers need for reproducible standard assays. Primary cells, by contrast, come directly from tissue and have a finite lifespan with more donor-to-donor variability, making them less reliable for standardization. In vivo tests are done in living organisms, not cultured cells, and in vitro tests describe the outside-the-body setting but don’t specify the unlimited growth feature that immortalized cells provide. So the statement about cells that can divide indefinitely used for standard assays is best described by immortalized cells.

The concept here is that some cell lines can keep dividing without hitting the normal aging limit, making them ideal for standard laboratory tests. Immortalized cells are altered so they bypass replicative senescence, often through mechanisms like telomerase activation or viral oncogene expression. This gives them a nearly endless supply and highly consistent behavior across many passages, which is exactly what researchers need for reproducible standard assays. Primary cells, by contrast, come directly from tissue and have a finite lifespan with more donor-to-donor variability, making them less reliable for standardization. In vivo tests are done in living organisms, not cultured cells, and in vitro tests describe the outside-the-body setting but don’t specify the unlimited growth feature that immortalized cells provide. So the statement about cells that can divide indefinitely used for standard assays is best described by immortalized cells.